When I was shooting for the mags, I had that scanner and VueScan. Best combination I came up with. Since I'm a software engineer by training, I built a bunch of stuff to automate it as much as possible. Using the Photoshop/Bridge batch capabilities is a huge time saver.
Definitely a good thing to learn but after the first few hundred you'll be banging your head against the wall.
is a lab in Denver that I've used for years starting when they were in LA. I'd recommend giving them a call and seeing what they can do for you.
Feel free to get in touch if you have specific questions. I probably have a few tips in the bottom of my head that may help.
FWIW, I decided awhile ago to only keep slides/negs that had been published and/or sold. I think I threw away over 10,000 slides and I don't even know how many sheets of 35mm B&W...